After receiving an S.O.S call, the Flying Orange speeds towards the planet Rengo. The surface of the friendly planet has been sprayed with a dangerous chemical plant formula by the deadly Dr. Plantro, rapidly causing the surface of the planet to be covered in dangerous weeds and plants. Tom and Oddball then head for the Doctor’s creepy island in space. They have to fight their way through bone-crunching trees and ferocious flowers to weed out the slippery crook and put an end to this growing peculiar problem.